Representativeness Math Example 4

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Example 4

hard
A clinical trial recruits patients from a university hospital. Explain why results may not be representative of the general patient population, and identify at least two characteristics that may differ.

Solution

  1. 1
    University hospital patients: often referred for complex/rare conditions; demographically skewed toward urban, educated populations near the university
  2. 2
    Characteristic 1: disease severity โ€” hospital patients may have more severe cases than average patients in the community
  3. 3
    Characteristic 2: demographics โ€” urban, higher socioeconomic status, near a teaching hospital โ€” may not represent rural or lower-income patients
  4. 4
    Implication: treatment effects found in this sample may not generalize to the broader patient population (limited external validity)

Answer

Hospital sample differs in severity and demographics; results may not generalize to all patients (external validity issue).
External validity asks: do results from this sample generalize to the target population? Convenience samples from specialized settings (university hospitals, prisons, university students) often lack representativeness, limiting the scope of conclusions.

About Representativeness

A sample is representative if its characteristics (distribution of key variables) closely match those of the population it is meant to represent.

Learn more about Representativeness โ†’

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